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Cell-Free DNA Preservation Tube

Cell-Free DNA Preservation Tube
Cell-Free DNA Preservation Tube
Cell-Free DNA Preservation Tube
Cell-Free DNA Preservation Tube
Cell-Free DNA Preservation Tube
Cell-Free DNA Preservation Tube

Technical Specifications

Tube type: Evacuated blood collection tube

Volume: 10 mL

Additive: Proprietary liquid stabilization reagent (colorless, clear)

Storage & Stability

  • Unopened tubes are stable at 4–30 °C until the expiration date printed on the label.
  • Do not freeze or expose to temperatures above 37 °C prior to use.
  • Once blood is collected, the stabilized sample can be held at 6–37 °C for up to 14 days without significant loss of cfDNA quality.

+86-755-2739 3226 info@chenyanglobal.com

Product Description

The Cell-Free DNA Preservation Tube is a direct-draw blood collection tube specifically designed to stabilize cell-free DNA (cfDNA) in whole blood at room temperature. Its proprietary, formaldehyde-free additive immediately prevents cell lysis and nuclease activity, effectively inhibiting the release of contaminating genomic DNA (gDNA) from nucleated blood cells. This ensures that the original cfDNA profile – both in concentration and integrity – is preserved from venipuncture all the way to downstream analysis.

By removing the need for immediate plasma separation and cold-chain transport, the tube simplifies complex pre-analytical workflows in liquid biopsy, non-invasive prenatal testing (NIPT), oncology research, and transplant monitoring. Whether samples are processed within hours or after days at ambient temperature, you obtain high-quality cfDNA that faithfully represents the in vivo circulating nucleic acid population.

Key Features & Benefits

FeatureBenefit
Room-temperature stabilization for up to 14 daysNo need for refrigeration or immediate plasma processing; supports remote collection, multi-center trials, and flexible laboratory schedules.
Minimal gDNA contaminationPrevents leukocyte lysis and limits gDNA release to <2% of total DNA throughout the stability window, ensuring robust allele frequency measurements and copy-number analysis.
Formaldehyde-free, non-toxic additiveSafe for users and fully compatible with standard enzymatic reactions (qPCR, digital PCR, NGS library preparation) without additional purification.
Consistent cfDNA recovery≥95% of original cfDNA yield maintained after 7 days and ≥90% after 14 days at 15–25 °C.
Validated for downstream applicationsDemonstrated performance in low-pass whole-genome sequencing, targeted NGS panels, ddPCR mutation detection, and bisulfite conversion-based methylation assays.
Ready-to-use vacuum tubeStandard blood collection format; simple inversion mixing protocol; compatible with routine phlebotomy practices.
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