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View detailsCell-Free DNA Preservation Tube
Cell-Free DNA Preservation Tube
Technical Specifications
Tube type: Evacuated blood collection tube
Volume: 10 mL
Additive: Proprietary liquid stabilization reagent (colorless, clear)
Storage & Stability
- Unopened tubes are stable at 4–30 °C until the expiration date printed on the label.
- Do not freeze or expose to temperatures above 37 °C prior to use.
- Once blood is collected, the stabilized sample can be held at 6–37 °C for up to 14 days without significant loss of cfDNA quality.
PRODUCT DETAIL
INQUIRY
Product Description
The Cell-Free DNA Preservation Tube is a direct-draw blood collection tube specifically designed to stabilize cell-free DNA (cfDNA) in whole blood at room temperature. Its proprietary, formaldehyde-free additive immediately prevents cell lysis and nuclease activity, effectively inhibiting the release of contaminating genomic DNA (gDNA) from nucleated blood cells. This ensures that the original cfDNA profile – both in concentration and integrity – is preserved from venipuncture all the way to downstream analysis.
By removing the need for immediate plasma separation and cold-chain transport, the tube simplifies complex pre-analytical workflows in liquid biopsy, non-invasive prenatal testing (NIPT), oncology research, and transplant monitoring. Whether samples are processed within hours or after days at ambient temperature, you obtain high-quality cfDNA that faithfully represents the in vivo circulating nucleic acid population.
Key Features & Benefits
| Feature | Benefit |
|---|---|
| Room-temperature stabilization for up to 14 days | No need for refrigeration or immediate plasma processing; supports remote collection, multi-center trials, and flexible laboratory schedules. |
| Minimal gDNA contamination | Prevents leukocyte lysis and limits gDNA release to <2% of total DNA throughout the stability window, ensuring robust allele frequency measurements and copy-number analysis. |
| Formaldehyde-free, non-toxic additive | Safe for users and fully compatible with standard enzymatic reactions (qPCR, digital PCR, NGS library preparation) without additional purification. |
| Consistent cfDNA recovery | ≥95% of original cfDNA yield maintained after 7 days and ≥90% after 14 days at 15–25 °C. |
| Validated for downstream applications | Demonstrated performance in low-pass whole-genome sequencing, targeted NGS panels, ddPCR mutation detection, and bisulfite conversion-based methylation assays. |
| Ready-to-use vacuum tube | Standard blood collection format; simple inversion mixing protocol; compatible with routine phlebotomy practices. |
“HCY, Health care for you” is our forever mission. We dedicate to offering safe & reliable products and medical services with our global creditable partners. HCY has already supplied to WHO, MAYO clinic, MGI, DDC, Yale University, Qorvo, Quanterix, Thomas Scientific, SD biosensor, Cardinal Health, Cleveland Clinic, Mars Petcare & LumiraDx, etc. in the past years.
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