Diverse Applications of DNA Polymerases from Shenzhen Huachenyang Technology Co., Ltd

DNA polymerases, as key enzymes responsible for DNA replication and repair in living organisms, play an indispensable role in life science research and numerous practical application fields. Shenzhen Huachenyang Technology Co., Ltd., with its advanced technology, has developed DNA polymerases with excellent performance, which are widely used in many important areas.​

The Cornerstone of Molecular Biology Research​

In molecular biology research, Polymerase Chain Reaction (PCR) is a core technology, and DNA polymerase is a crucial element of PCR technology. Take Huachenyang’s Pfu DNA polymerase as an example. Derived from the thermophilic bacterium Pyrococcus furiosus and modified through gene mutation and recombination, it has extremely high thermal stability and . In high-fidelity PCR amplification experiments, its 3’ to 5’ exonuclease activity can correct errors in real-time, significantly reducing the mutation rate. Its fidelity is 10 times higher than that of Taq DNA polymerase and more outstanding than common high-fidelity DNA polymerases such as Vent, DeepVent, Pwo, and Tli. This enables researchers to obtain highly accurate products when amplifying gene fragments, laying a solid foundation for subsequent experiments such as gene function research, gene cloning, and gene library construction, and assisting scientists in exploring the genetic code of life in depth.​

A Powerful Weapon for Disease Diagnosis​

In the field of disease diagnosis, DNA polymerase plays a vital role. In the diagnosis of genetic diseases, Huachenyang’s Taq DNA polymerase can highly accurately recognize and bind to bases, precisely amplifying relevant gene fragments, helping doctors determine whether patients carry pathogenic genes and providing key evidence for the early diagnosis and intervention of genetic diseases. In tumor disease research, detecting specific gene mutations in tumor cells can assist doctors in formulating refined treatment plans. Moreover, in virus infection detection, such as AIDS and monkeypox virus detection, combined with Huachenyang’s independently developed DNA polymerase with high inhibitor tolerance, it has the advantages of direct amplification of samples without extraction, accelerating virus load detection and disease diagnosis, and gaining precious time for epidemic prevention and control.​

A Key Aid in Forensic Identification​

In forensic identification work, DNA polymerase is also an indispensable tool. At the scene of criminal cases, such as trace amounts of bloodstains and hairs found at the scene of a homicide, Huachenyang’s PCR polymerase is used to amplify the DNA therein, and then compared with the suspect’s DNA fingerprint, which can provide key clues for solving the case and become powerful evidence for identifying criminals. In the scenario of paternity testing, PCR polymerase is also relied on to amplify and analyze the relevant DNA, resolve family disputes, determine kinship, and restore the truth.​

Extensive Applications in Other Fields​

In the field of microbial research, when studying the structure of soil microbial communities, Huachenyang’s PCR polymerase can amplify specific gene fragments of bacteria and other microorganisms, helping to reveal the functions and stability of the soil ecosystem. In food safety testing, when detecting pathogenic bacteria in meat products, it can provide reliable test results in a short time, safeguarding the safety of consumers’ dining tables. In the field of plant protection and improvement, when studying new plant viruses, it can successfully amplify the virus gene sequences, providing key information for the development of prevention and control measures; in crop gene improvement, it helps researchers accurately amplify gene fragments related to excellent traits, accelerating the breeding process. For example, it plays an important role in the research on improving the lodging resistance of wheat.​

The DNA polymerases of Shenzhen Huachenyang Technology Co., Ltd., with their excellent performance, have demonstrated strong application values in multiple fields, providing important support for scientific research, disease prevention and control, judicial justice, ecological protection, and agricultural development, promoting the continuous progress of various fields and continuously contributing to the progress of human society.